Article
Therapeutic target discovery using Caenorhabditis elegans.
Pharmacogenomics - 1 May 2000
Link E M, Hardiman G, Sluder A E, Johnson C D, Liu L X
Abstract excerpt
Use of the human genome sequence in disease therapy will require efficient identification of disease-causing and disease-associated genes with functions that are amenable to pharmacological manipulation. The validation and development of such genes as therapeutic targets requires information about both the genes' functions and the biochemical pathways in which they participate. One powerful means of obtaining...
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