Article
Angiotensin receptor type 1 single nucleotide polymorphism 1166A/C is associated with malignant arrhythmias and altered circulating miR-155 levels in patients with chronic heart failure.
Journal of cardiac failure - 1 Sept 2012
Blanco Raul R, Austin Harland, Vest Richard N, Valadri Ravinder, Li Wei, Lassegue Bernard, Song Qing, London Barry, Dudley Samuel C, Bloom Heather L, Searles Charles D, Zafari A Maziar
Abstract excerpt
BACKGROUND: Sudden cardiac death (SCD) from ventricular tachyarrhythmias accounts for approximately 450,000 annual deaths in the United States; many of these cases involve patients with chronic heart failure (HF). Prediction of which HF patients are most susceptible to SCD is difficult, and it is uncertain whether gene polymorphisms associated with HF outcomes are also linked to arrhythmic risk. METHODS: We...
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