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Article

Effects of AGTR1 A1166C gene polymorphism in patients with heart failure treated with candesartan.

The Annals of pharmacotherapy - 1 Jul 2008

de Denus Simon, Zakrzewski-Jakubiak Marcin, Dubé Marie-Pierre, Bélanger François, Lepage Serge, Leblanc Marie-Hélène, Gossard Denis, Ducharme Anique, Racine Normand, Whittom Lucette, Lavoie Joel, Touyz Rhian M, Turgeon Jacques, White Michel

Abstract excerpt

BACKGROUND: The benefits of angiotensin II receptor blockers (ARBs) in patients with heart failure who are treated with standard pharmacotherapy, including an angiotensin-converting enzyme (ACE) inhibitor, were demonstrated in 2 large randomized trials. It is currently impossible to determine which patient will benefit from the addition of an ARB. OBJECTIVE: To explore the impact of selected candidate genes on...

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Source

Identifiers

PMID: 18594050
DOI: 10.1345/aph.1K657

Genes

ACE
AGTR1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Effects of AGTR1 A1166C gene polymorphism in patients with heart failure treated with candesartan.PMID 18594050Read ↗

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AT1 receptor A/C1166 polymorphism contributes to cardiac hypertrophy in subjects with hypertrophic cardiomyopathy.Semantic proximity Read ↗

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