Article
Interplay between miR-155, AT1R A1166C polymorphism, and AT1R expression in young untreated hypertensives.
American journal of hypertension - 1 Feb 2011
Ceolotto Giulio, Papparella Italia, Bortoluzzi Alessia, Strapazzon Giacomo, Ragazzo Fabio, Bratti Paolo, Fabricio Aline S C, Squarcina Elisa, Gion Massimo, Palatini Paolo, Semplicini Andrea
Abstract excerpt
BACKGROUND: A silent polymorphism (+1166 A/C single-nucleotide polymorphism) localized in the 3'-UTR (untranslated region) of the human angiotensin II type-1 receptor (AT1R) has been associated with hypertension and cardiovascular complications. The +1166 A/C is recognized by a specific microRNA-...
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