Article
Biological characterization of human immunodeficiency virus type 1 subtype C protease carrying indinavir drug-resistance mutations.
The Journal of general virology - 1 May 2006
Gonzalez Luis M F, Aguiar Renato S, Afonso Adriana, Brindeiro Patricia A, Arruda Mônica B, Soares Marcelo A, Brindeiro Rodrigo M, Tanuri Amílcar
Abstract excerpt
Human immunodeficiency virus type 1 subtype C isolates belong to one of the most prevalent strains circulating worldwide and are responsible for the majority of new infections in the sub-Saharan region and other highly populated areas of the globe. In this work, the impact of drug-resistance mutations in the protease gene of subtype C viruses was analysed and compared with that of subtype B counterparts. A series...
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