Article
Pharmacologic evidence to support clinical decision making for peripartum methadone treatment.
Psychopharmacology - 1 Jan 2013
Bogen D L, Perel J M, Helsel J C, Hanusa B H, Romkes M, Nukui T, Friedman C R, Wisner K L
Abstract excerpt
RATIONALE: Limited pharmacological data are available to guide methadone treatment during pregnancy and postpartum. OBJECTIVES: Study goals were to (1) characterize changes in methadone dose across childbearing, (2) determine enantiomer-specific methadone withdrawal kinetics from steady state dur...
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