Article
Single nucleotide polymorphisms in the interleukin-6 gene associated with blood pressure and atherosclerosis in a Japanese general population.
Hypertension research : official journal of the Japanese Society of Hypertension - 1 Jan 2005
Tanaka Chihiro, Mannami Toshifumi, Kamide Kei, Takiuchi Shin, Kokubo Yoshihiro, Katsuya Tomohiro, Kawano Yuhei, Miyata Toshiyuki, Ogihara Toshio, Tomoike Hitonobu
Abstract excerpt
It is known that increased plasma levels of inflammatory markers, such as interleukin-6 (IL-6), are associated with atherosclerosis and myocardial infarction. The aim of this study was to reveal the contribution of the single nucleotide polymorphisms (SNPs) of the IL-6 gene on the blood pressure regulation and progression of atherosclerosis in a general Japanese population. In order to evaluate the potential...
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