Article
Interleukin-6 -634C>G polymorphism in hypertensive patients with and without left ventricular hypertrophy.
Molecular medicine reports - 1 Jan 2000
Chen Feng, Guo Jing, Gao Shu-Ping, Chen Chu, Guo Yun-Feng, Gui Le, Geng Hai-Hua, Ge Li-Jun, Zhu Jian-Hua, Pan Min
Abstract excerpt
There is an accumulating body of evidence indicating that inflammation plays a pivotal role in the pathogenesis of cardiovascular disease. Interleukin-6 (IL-6) is a pleiotropic cytokine secreted by many cells of the immune system, cardiovascular components and adipose tissue, and functions as a mediator of inflammatory response with both pro- and anti-inflammatory properties. Circulating levels of IL-6 differ...
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