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Elevated interleukin-36γ and gene polymorphisms implicate novel risk in essential hypertension.

Immunogenetics - 6 Jul 2026

Kainat Alishba, Mian Fazlul Aziz, Khan Muhammad Asif Nawaz, Nasim Mubeen Tabish, Nurulain Syed Muhammad, Bibi Nazia, Shah Syed Tahir Abbas, Khan Muhammad Jadoon, Hussain Sabir

Abstract excerpt

Cytokines are crucial in regulating hypertension and vascular inflammation. The clinical significance of circulating IL-36γ levels and IL36G gene variants in relation to essential hypertension risk was assessed because IL-36γ has been associated with several cardiovascular diseases, while its role in essential hypertension is still unknown. Serum IL-36γ levels were determined by enzyme-linked immunosorbent assay,...

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Case-Control Studies
Essential Hypertension
Genetic Association Studies
Haplotypes
Hypertension

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

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Identifiers

PMID: 42402508
DOI: 10.1007/s00251-026-01410-5

Genes

IL36G
TG

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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