Article
Pooled DNA resequencing of 68 myocardial infarction candidate genes in French canadians.
Circulation. Cardiovascular genetics - 1 Oct 2012
Beaudoin Mélissa, Lo Ken Sin, N'Diaye Amidou, Rivas Manuel A, Dubé Marie-Pierre, Laplante Nathalie, Phillips Michael S, Rioux John D, Tardif Jean-Claude, Lettre Guillaume
Abstract excerpt
BACKGROUND: Familial history is a strong risk factor for coronary artery disease (CAD), especially for early-onset myocardial infarction (MI). Several genes and chromosomal regions have been implicated in the genetic cause of coronary artery disease/MI, mostly through the discovery of familial mutations implicated in hyper-/hypocholesterolemia by linkage studies and single nucleotide polymorphisms by genome-wide...
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