Article
Refined mapping of a quantitative trait locus on chromosome 1 responsible for mouse embryonic death.
PloS one - 1 Jan 2012
Vatin Magalie, Burgio Gaetan, Renault Gilles, Laissue Paul, Firlej Virginie, Mondon Françoise, Montagutelli Xavier, Vaiman Daniel, Serres Catherine, Ziyyat Ahmed
Abstract excerpt
Recurrent spontaneous abortion (RSA) is defined as the loss of three or more consecutive pregnancies during the first trimester of embryonic intrauterine development. This kind of human infertility is frequent among the general population since it affects 1 to 5% of women. In half of the cases the etiology remains unelucidated. In the present study, we used interspecific recombinant congenic mouse strains (IRCS)...
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