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Centimorgan-Range One-Step Mapping of Fertility Traits Using Interspecific Recombinant Congenic Mice

5 May 2007

Abstract excerpt

In mammals, male fertility is a quantitative feature determined by numerous genes. Until now, several wide chromosomal regions involved in fertility have been defined by genetic mapping approaches; unfortunately, the underlying genes are very difficult to identify. Here, 53 interspecific recombinant congenic mouse strains (IRCSs) bearing 1-2% SEG/Pas (Mus spretus) genomic fragments disseminated in a C57Bl/6J (Mus...

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PMID: 17483418
DOI: 10.1534/genetics.107.072157

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