Article
A High-Resolution Genetic Map for the Laboratory Rat.
G3 (Bethesda, Md.) - 2 Jul 2018
Littrell John, Tsaih Shirng-Wern, Baud Amelie, Rastas Pasi, Solberg-Woods Leah, Flister Michael J
Abstract excerpt
An accurate and high-resolution genetic map is critical for mapping complex traits, yet the resolution of the current rat genetic map is far lower than human and mouse, and has not been updated since the original Jensen-Seaman map in 2004. For the first time, we have refined the rat genetic map to sub-centimorgan (cM) resolution (<0.02 cM) by using 95,769 genetic markers and 870 informative meioses from a cohort...
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