Article
Association of FOXD1 variants with adverse pregnancy outcomes in mice and humans.
Open biology - 1 Oct 2016
Laissue Paul, Lakhal Besma, Vatin Magalie, Batista Frank, Burgio Gaëtan, Mercier Eric, Santos Esther Dos, Buffat Christophe, Sierra-Diaz Diana Carolina, Renault Gilles, Montagutelli Xavier, Salmon Jane, Monget Philippe, Veitia Reiner A, Méhats Céline, Fellous Marc, Gris Jean-Christophe, Cocquet Julie, Vaiman Daniel
Abstract excerpt
Recurrent spontaneous abortion (RSA) is a common cause of infertility, but previous attempts at identifying RSA causative genes have been relatively unsuccessful. Such failure to describe RSA aetiological genes might be explained by the fact that reproductive phenotypes should be considered as quantitative traits resulting from the intricate interaction of numerous genetic, epigenetic and environmental factors....
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