Article
Identification of Quantitative Trait Loci responsible for embryonic lethality in mice assessed by ultrasonography.
The International journal of developmental biology - 1 Jan 2009
Laissue Paul, Burgio Gaétan, l'Hôte David, Renault Gilles, Marchiol-Fournigault Carmen, Fradelizi Didier, Fellous Marc, Serres Catherine, Montagutelli Xavier, Monget Philippe, Vaiman Daniel
Abstract excerpt
Recurrent Spontaneous Abortion (RSA) is a frequent pathology affecting 1 to 5% of couples. In approximately 50 % of cases, the aetiology is unknown suggesting a subtle interaction between genetic and environmental factors. Previous attempts to describe genetic factors using the candidate gene approach have been relatively unsuccessful due to the physiological, cellular and genetic complexity of mammalian...
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