Article
Localization of a region in the fusion protein of avian metapneumovirus that modulates cell-cell fusion.
Journal of virology - 1 Nov 2012
Wei Yongwei, Feng Kurtis, Yao Xiangjie, Cai Hui, Li Junan, Mirza Anne M, Iorio Ronald M, Li Jianrong
Abstract excerpt
The genus Metapneumovirus within the subfamily Pneumovirinae of the family Paramyxoviridae includes two members, human metapneumovirus (hMPV) and avian metapneumovirus (aMPV), causing respiratory tract infections in humans and birds, respectively. Paramyxoviruses enter host cells by fusing the viral envelope with a host cell membrane. Membrane fusion of hMPV appears to be unique, in that fusion of some hMPV...
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