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Breaking In: Human Metapneumovirus Fusion and Entry

16 Jan 2013

Abstract excerpt

Human metapneumovirus (HMPV) is a leading cause of respiratory infection that causes upper airway and severe lower respiratory tract infections. HMPV infection is initiated by viral surface glycoproteins that attach to cellular receptors and mediate virus membrane fusion with cellular membranes. Most paramyxoviruses use two viral glycoproteins to facilitate virus entry-an attachment protein and a fusion (F)...

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PMID: 23325326
DOI: 10.3390/v5010192

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