Article
Characterization of human metapneumovirus F protein-promoted membrane fusion: critical roles for proteolytic processing and low pH.
Journal of virology - 1 Nov 2006
Schowalter Rachel M, Smith Stacy E, Dutch Rebecca Ellis
Abstract excerpt
Human metapneumovirus (HMPV) is a recently described human pathogen of the pneumovirus subfamily within the paramyxovirus family. HMPV infection is prevalent worldwide and is associated with severe respiratory disease, particularly in infants. The HMPV fusion protein (F) amino acid sequence contains features characteristic of other paramyxovirus F proteins, including a putative cleavage site and potential...
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