Article
Lack of β2-AR improves exercise capacity and skeletal muscle oxidative phenotype in mice.
Scandinavian journal of medicine & science in sports - 1 Dec 2012
Voltarelli V A, Bacurau A V N, Bechara L R G, Bueno C R, Bozi L H M, Mattos K C, Salemi V M C, Brum P C
Abstract excerpt
β(2)-adrenergic receptor (β(2)-AR) agonists have been used as ergogenics by athletes involved in training for strength and power in order to increase the muscle mass. Even though anabolic effects of β(2)-AR activation are highly recognized, less is known about the impact of β(2)-AR in endurance capacity. We presently used mice lacking β(2)-AR [β(2)-knockout (β(2) KO)] to investigate the role of β(2)-AR on...
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