Article
Extensive in vivo resilience of persistent Salmonella.
PloS one - 1 Jan 2012
Barat Somedutta, Steeb Benjamin, Mazé Alain, Bumann Dirk
Abstract excerpt
Chronic infections caused by persistent pathogens represent an important health problem. Here, we establish a simple practical mouse Salmonella infection model for identifying bacterial maintenance functions that are essential for persistency. In this model, a substantial fraction of Salmonella survived even several days of treatment with a potent fluoroquinolone antibiotic indicating stringency of the model....
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