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Article

Genome-wide screen for Salmonella genes required for long-term systemic infection of the mouse.

PLoS pathogens - 1 Feb 2006

Lawley Trevor D, Chan Kaman, Thompson Lucinda J, Kim Charles C, Govoni Gregory R, Monack Denise M

Abstract excerpt

A microarray-based negative selection screen was performed to identify Salmonella enterica serovar Typhimurium (serovar Typhimurium) genes that contribute to long-term systemic infection in 129X1/SvJ (Nramp1(r)) mice. A high-complexity transposon-mutagenized library was used to infect mice intraperitoneally, and the selective disappearance of mutants was monitored after 7, 14, 21, and 28 d postinfection. One...

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Source

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Identifiers

PMID: 16518469
DOI: 10.1371/journal.ppat.0020011
PMCID: PMC1383486

Genes

SPI1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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