Article
Differential outcome of infection with attenuated Salmonella in MyD88-deficient mice is dependent on the route of administration.
Immunobiology - 1 Jan 2013
Issac Jincy M, Sarawathiamma Dhanya, Al-Ketbi Mai I, Azimullah Sheikh, Al-Ojali Samia M, Mohamed Yassir A, Flavell Richard A, Fernandez-Cabezudo Maria J, al-Ramadi Basel K
Abstract excerpt
Activation of the innate immune system is a prerequisite for the induction of adaptive immunity to both infectious and non-infectious agents. TLRs are key components of the innate immune recognition system and detect pathogen-associated molecular patterns. Most TLRs utilize the MyD88 adaptor for their signaling pathways. In the current study, we investigated innate and adaptive immune responses to primary as well...
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