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Article

Genetic variations of the NR3A subunit of the NMDA receptor modulate prefrontal cerebral activity in humans.

Journal of cognitive neuroscience - 1 Jan 2007

Gallinat Jürgen, Götz Thomas, Kalus Peter, Bajbouj Malek, Sander Thomas, Winterer Georg

Abstract excerpt

INTRODUCTION: Recently, a novel N-methyl-D-aspartate (NMDA) receptor subunit, NR3A, has been discovered in the brain. This subunit decreases NMDA receptor activity by modulating the calcium permeability of the receptor channel and current density in cortical cells. Because the NR3A is expressed in the human prefrontal cortex, we hypothesized that genetic variations of the NR3A subunit modulate prefrontal...

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Identifiers

PMID: 17214563
DOI: 10.1162/jocn.2007.19.1.59

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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