Article
Functional Genomics and Insights into the Pathogenesis and Treatment of Psoriasis.
Biomolecules - 3 May 2024
Shellard Elan May, Rane Shraddha S, Eyre Stephen, Warren Richard B
Abstract excerpt
Psoriasis is a lifelong, systemic, immune mediated inflammatory skin condition, affecting 1-3% of the world's population, with an impact on quality of life similar to diseases like cancer or diabetes. Genetics are the single largest risk factor in psoriasis, with Genome-Wide Association (GWAS) studies showing that many psoriasis risk genes lie along the IL-23/Th17 axis. Potential psoriasis risk genes determined...
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