Article
Oxidative DNA damage is important to the evolution of antibiotic resistance: evidence of mutation bias and its medicinal implications.
Journal of biomolecular structure & dynamics - 1 Jan 2013
Wang Zhong-Yi, Xiong Min, Fu Liang-Yu, Zhang Hong-Yu
Abstract excerpt
Several (1) studies have revealed that the reactive oxygen species (ROS) induced by antibacterial stimulation accelerates the evolution of antibiotic resistance, which uncovered new links between oxygen rise and evolution and inspired new strategies to prevent antibiotic resistance. Considering many other mechanisms cause DNA mutations aside from ROS damage, evaluating the significance of oxidative DNA damage in...
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