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Article

An evolutionary explanation for antibiotics’ association with increased colon cancer risk

1 Jan 2022

Abstract excerpt

: More than 10 studies have confirmed the association of antibiotic overuse with colorectal cancer. The exact cause is unknown, but most authors hypothesize that disturbance of colon microbiota is the main culprit. In this commentary, an evolutionary explanation is proposed. It is well known that antibiotics can induce antibiotic resistance in bacteria through selection of mutators-DNA mismatch repair deficient...

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PMID: 35539898
DOI: 10.1093/emph/eoac018

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