Article
The role of intracellular ROS in the development of antimicrobial resistance:A convergent mediator linking mutations and horizontal gene transfer.
Environmental pollution (Barking, Essex : 1987) - 1 Oct 2026
Zhang Yao, Ren Chong-Yang, Cao Xiaoqiang, Zhao He-Ping
Abstract excerpt
The development of antimicrobial resistance (AMR) is a major threat to global public health and environmental security. While antibiotics are known drivers, a wide range of non-antibiotic pollutants also promote antibiotic resistance genes (ARG) dissemination, yet the underlying unifying mechanism remains poorly integrated. This paper systematically analyzes how reactive oxygen species (ROS) act as major...
Topics
- Gene Transfer, Horizontal
- Reactive Oxygen Species
- Mutation
- Drug Resistance, Microbial
- Drug Resistance, Bacterial
- Anti-Bacterial Agents
- Bacteria
- Oxidative Stress