Article
Functional polymorphisms in the promoter of the matrix metalloproteinase-9 (MMP-9) gene are not linked with significant plasma MMP-9 variations in healthy subjects.
Clinical chemistry and laboratory medicine - 1 Jan 2008
Demacq Caroline, Vasconcellos Vivian B, Marcaccini Andrea M, Gerlach Raquel F, Silva Wilson A, Tanus-Santos Jose E
Abstract excerpt
BACKGROUND: Matrix metalloproteinase-9 (MMP-9) is involved in the degradation of the extracellular matrix during physiological and pathological processes. Two functional polymorphisms [C(-1562)T and microsatellite (CA)13-25] in the promoter region of the MMP-9 gene have been associated with several diseases. The aim of this study was to examine whether these MMP-9 polymorphisms and haplotypes are linked with...
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