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Article

The tumor suppressive role of miRNA-370 by targeting FoxM1 in acute myeloid leukemia

17 Aug 2012

Abstract excerpt

BACKGROUND: Recent evidence has accumulated that MicroRNA (miRNA) dysregulation occurs in the majority of human malignancies including acute myeloid leukemia (AML) and may contribute to onco-/leukemo-genesis. METHODS: The expression levels of miR-370 and FoxM1 were assessed in 48 newly diagnosed AML patients, 40 AML patients in 1st complete remission (CR) and 21 healthy controls. Quantitative real-time PCR,...

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PMID: 22900969
DOI: 10.1186/1476-4598-11-56

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