Article
Overexpression of miR-378 is frequent and may affect treatment outcomes in patients with acute myeloid leukemia.
Leukemia research - 1 Jul 2013
Qian Jun, Lin Jiang, Qian Wei, Ma Ji-chun, Qian Si-xuan, Li Yun, Yang Jing, Li Jian-yong, Wang Cui-zhu, Chai Hai-yan, Chen Xing-xing, Deng Zhao-qun
Abstract excerpt
MicroRNA miR-378 plays important roles in tumorigenesis by enhancing cell survival, reducing apoptosis, promoting tumor growth, angiogenesis and promoting cell migration and invasion. Abnormal expression of miR-378 has been observed in various types of cancers. The aim of this study was to investigate the expression status of miR-378 and its clinical significance in patients with acute myeloid leukemia (AML)...
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