Down-Regulation of miR-186 Correlates with Poor Survival in de novo Acute Myeloid Leukemia.

Abstract excerpt

BACKGROUND: MicroRNA-186 (miR-186) plays an important role in the pathogenesis of several cancers. Our study was intended to investigate the expression status and the prognostic implication of miR-186 in acute myeloid leukemia (AML). METHODS: Real-time quantitative PCR was carried out in 112 de novo AML patients and 28 controls. RESULTS: The level of miR-186 expression in AML was significantly down-regulated...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to CCAAT-Enhancer-Binding Proteins
• Share to Down-Regulation