Article
Influence of anatomical subsite on the incidence of microsatellite instability, and KRAS and BRAF mutation rates in patients with colon carcinoma.
Pathology, research and practice - 15 Oct 2012
Benedix Frank, Meyer Frank, Kube Rainer, Kropf Siegfried, Kuester Doerthe, Lippert Hans, Roessner Albert, Krüger Sabine
Abstract excerpt
There is a growing amount of data supporting the concept that cancers originating from the proximal and distal colon are distinct clinicopathological entities. The incidence of MSI and BRAF mutation is strongly associated with right sided tumor location, whereas there are conflicting results for KRAS mutation rates. However, to date, no data exist whether and to what extent defined colonic subsites influence MSI...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.