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Article

Clinicopathological and protein characterization of BRAF- and K-RAS-mutated colorectal cancer and implications for prognosis.

International journal of cancer - 15 Jul 2010

Zlobec Inti, Bihl Michel P, Schwarb Heike, Terracciano Luigi, Lugli Alessandro

Abstract excerpt

Recent evidence highlights the potential prognostic and predictive value of BRAF and K-RAS gene alterations in patients with colorectal cancer. However, a comprehensive evaluation of BRAF and K-RAS mutations and their specific clinicopathological features, histomorphological presentation and effect on protein expression have not been systematically analyzed. The aim of this study was to characterize the...

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Source

Identifiers

PMID: 19908233
DOI: 10.1002/ijc.25042

Genes

BRAF
CDX2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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