Article
Stargazer: a new neurological mutant on chromosome 15 in the mouse with prolonged cortical seizures.
Epilepsy research - 1 Nov 1990
Noebels J L, Qiao X, Bronson R T, Spencer C, Davisson M T
Abstract excerpt
We report here the initial description of the inheritance pattern, linkage mapping, and electroclinical phenotype of a recessive mutation on mouse Chromosome 15, stargazer (stg), that produces epilepsy. The salient epileptic phenotype is a syndrome of spontaneous, prolonged, generalized spike-wave cortical discharges with behavioral arrest. A second, complex, seizure pattern featuring movements during the...
Topics
- Animals
- Cerebral Cortex
- Chromosomes
- Electroencephalography
- Female
- Genetic Linkage
- Male
- Mice
- Mice, Neurologic Mutants
- Phenotype
- Seizures
- Time Factors
