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Article

Single-gene models of epilepsy.

Advances in neurology - 1 Jan 1999

Noebels J L

Abstract excerpt

Single-gene models of epilepsy present valuable opportunities to isolate and experimentally reproduce gene mutations for human seizure disorders, to test molecular mechanisms of epileptogenesis, and to explore strategies to correct early hyperexcitability defects in the developing brain. Although not all inherited epilepsies are monogenic, analysis of epileptic phenotypes in spontaneous and transgenic mouse...

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PMID: 10514817

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