Article
Structural analysis of the envelope gp120 V3 loop for some HIV-1 variants circulating in the countries of Eastern Europe.
Journal of biomolecular structure & dynamics - 1 Jan 2013
Andrianov Alexander M, Kornoushenko Yuri V, Anishchenko Ivan V, Eremin Vladimir F, Tuzikov Alexander V
Abstract excerpt
The V3 loop on gp120 from human immunodeficiency virus type 1 (HIV-1) is a focus of many research groups involved in anti-AIDS drug development because this region of the protein is a principal target for neutralizing antibodies and a major determinant for cell tropism and syncytium formation. In this study, the nucleotide sequences of the env gene region coding the V3 loop were determined by DNA sequencing...
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