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Article

Identification of the principal neutralizing determinant of human immunodeficiency virus type 1 as a fusion domain

1 Jan 1991

Abstract excerpt

The V3 loop, located near the middle of the surface envelope glycoprotein gp120, is the major neutralizing domain of human immunodeficiency virus type 1 (HIV-1). Although the majority of the V3 loop is highly variable between different strains of HIV-1, a Gly-Pro-Gly-Arg motif at the tip of the loop is highly conserved. To determine whether this region plays a role in fusion mediated by the HIV-1 envelope...

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Identifiers

PMID: 1985197
DOI: 10.1128/jvi.65.1.190-194.1991

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Identification of the principal neutralizing determinant of human immunodeficiency virus type 1 as a fusion domainPMID 1985197Read ↗

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