Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Protein and DNA-sequence homologies between the V3-loop of human immunodeficiency virus type I envelope protein gp120 and immunoglobulin variable regions.

Biochemical and biophysical research communications - 16 Sept 1991

Metlas R, Veljkovic V, Paladini R D, Pongor S

Abstract excerpt

We found that a common amino acid sequence motif exists between the V3-loop region of the human immunodeficiency virus type I envelope protein HIV gp120 and the human immunoglobulin heavy chain variable regions of subclass III (Ig VH-III). In the Ig VH-III sequences, the common motif overlaps wit...

Topics

Amino Acid Sequence
Base Sequence
Consensus Sequence
DNA, Viral
Genes, Immunoglobulin
Genetic Variation
HIV Envelope Protein gp120
HIV-1
Molecular Sequence Data
Sequence Alignment
Sequence Homology, Nucleic Acid

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 1898386
DOI: 10.1016/0006-291x(91)91926-4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1898386-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Protein and DNA-sequence homologies between the V3-loop of human immunodeficiency virus type I envelope protein gp120 and immunoglobulin variable regions.PMID 1898386Read ↗

Sequence variation and consensus sequence of V3 loop on HIV-1 gp120.Semantic proximity Read ↗

Structural analysis of the envelope gp120 V3 loop for some HIV-1 variants circulating in the countries of Eastern Europe.Semantic proximity Read ↗

Hypervariable region 3 residues of HIV type 1 gp120 involved in CCR5 coreceptor utilization: therapeutic and prophylactic implications.Semantic proximity Read ↗

Low complexity regions (LCRs) contribute to the hypervariability of the HIV-1 gp120 protein.Semantic proximity Read ↗

A V3 Loop-Dependent gp120 Element Disrupted by CD4 Binding Stabilizes the Human Immunodeficiency Virus Envelope Glycoprotein TrimerSemantic proximity Read ↗

Structural conservation predominates over sequence variability in the crown of HIV type 1's V3 loop.Semantic proximity Read ↗

Structure of a V3-Containing HIV-1 gp120 CoreSemantic proximity Read ↗

Clade-specific differences between human immunodeficiency virus type 1 clades B and C: diversity and correlations in C3-V4 regions of gp120.Semantic proximity Read ↗

V3 loop of the human immunodeficiency virus type 1 Env protein: interpreting sequence variability.Semantic proximity Read ↗

Variability in the human immunodeficiency virus type 1 gp120 Env protein linked to phenotype-associated changes in the V3 loop.Semantic proximity Read ↗

Mutational trends in V3 loop protein sequences observed in different genetic lineages of human immunodeficiency virus type 1.Semantic proximity Read ↗

Relationship of the human immunodeficiency virus type 1 gp120 third variable loop to a component of the CD4 binding site in the fourth conserved region.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.