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Article

Current status of drug screening and disease modelling in human pluripotent stem cells.

BioEssays : news and reviews in molecular, cellular and developmental biology - 1 Mar 2013

Rajamohan Divya, Matsa Elena, Kalra Spandan, Crutchley James, Patel Asha, George Vinoj, Denning Chris

Abstract excerpt

The emphasis in human pluripotent stem cell (hPSC) technologies has shifted from cell therapy to in vitro disease modelling and drug screening. This review examines why this shift has occurred, and how current technological limitations might be overcome to fully realise the potential of hPSCs. Details are provided for all disease-specific human induced pluripotent stem cell lines spanning a dozen dysfunctional...

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Identifiers

PMID: 22886688
DOI: 10.1002/bies.201200053
PMCID: PMC3597971

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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