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Article

In vitro uses of human pluripotent stem cell-derived cardiomyocytes.

Journal of cardiovascular translational research - 1 Oct 2012

Matsa Elena, Denning Chris

Abstract excerpt

Functional cardiomyocytes can be efficiently derived from human pluripotent stem cells (hPSCs), which collectively include embryonic and induced pluripotent stem cells. This cellular platform presents exciting new opportunities for development of pharmacologically relevant in vitro screens to detect cardiotoxicity, validate novel drug candidates in preclinical trials and understand complex congenital...

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PMID: 22639342
DOI: 10.1007/s12265-012-9376-5

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