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Article

Induced pluripotent stem cells for modelling human diseases

4 Jul 2011

Abstract excerpt

Research into the pathophysiological mechanisms of human disease and the development of targeted therapies have been hindered by a lack of predictive disease models that can be experimentally manipulated in vitro. This review describes the current state of modelling human diseases with the use of human induced pluripotent stem (iPS) cell lines. To date, a variety of neurodegenerative diseases, haematopoietic...

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PMID: 21727133
DOI: 10.1098/rstb.2011.0017

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