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Complexity and developmental changes in the expression pattern of claudins at the blood–CSF barrier

10 Aug 2012

Abstract excerpt

The choroid plexus epithelium controls the movement of solutes between the blood and the cerebrospinal fluid. It has been considered as a functionally more immature interface during brain development than in adult. The anatomical basis of this barrier is the interepithelial choroidal junction whose tightness has been attributed to the presence of claudins. We used quantitative real-time polymerase chain reaction,...

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PMID: 22886143
DOI: 10.1007/s00418-012-1001-9

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