Article
Establishment of a neuroepithelial barrier by Claudin5a is essential for zebrafish brain ventricular lumen expansion.
Proceedings of the National Academy of Sciences of the United States of America - 26 Jan 2010
Zhang Jingjing, Piontek Jörg, Wolburg Hartwig, Piehl Christian, Liss Martin, Otten Cécile, Christ Annabel, Willnow Thomas E, Blasig Ingolf E, Abdelilah-Seyfried Salim
Abstract excerpt
Lumen expansion driven by hydrostatic pressure occurs during many morphogenetic processes. Although it is well established that members of the Claudin family of transmembrane tight junction proteins determine paracellular tightness within epithelial/endothelial barrier systems, functional evidence for their role in the morphogenesis of lumenized organs has been scarce. Here, we identify Claudin5a as a core...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.