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A transgenic zebrafish model for the in vivo study of the blood and choroid plexus brain barriers using claudin 5

2 Feb 2018

Abstract excerpt

ABSTRACT The central nervous system (CNS) has specific barriers that protect the brain from potential threats and tightly regulate molecular transport. Despite the critical functions of the CNS barriers, the mechanisms underlying their development and function are not well understood, and there are very limited experimental models for their study. Claudin 5 is a tight junction protein required for blood brain...

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PMID: 29437557
DOI: 10.1242/bio.030494

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