Article
Expression and phylogeny of claudins in vertebrate primordia.
Proceedings of the National Academy of Sciences of the United States of America - 28 Aug 2001
Kollmar R, Nakamura S K, Kappler J A, Hudspeth A J
Abstract excerpt
Claudins, the major transmembrane proteins of tight junctions, are members of the tetraspanin superfamily of proteins that mediate cellular adhesion and migration. Their functional importance is demonstrated by mutations in claudin genes that eliminate tight junctions in myelin and the testis, abolish Mg(2+) resorption in the kidney, and cause autosomal recessive deafness. Here we report that two paralogs among...
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