Article
Genome-wide association study of multiplex schizophrenia pedigrees.
The American journal of psychiatry - 1 Sept 2012
Levinson Douglas F, Shi Jianxin, Wang Kai, Oh Sang, Riley Brien, Pulver Ann E, Wildenauer Dieter B, Laurent Claudine, Mowry Bryan J, Gejman Pablo V, Owen Michael J, Kendler Kenneth S, Nestadt Gerald, Schwab Sibylle G, Mallet Jacques, Nertney Deborah, Sanders Alan R, Williams Nigel M, Wormley Brandon, Lasseter Virginia K, Albus Margot, Godard-Bauché Stephanie, Alexander Madeline, Duan Jubao, O'Donovan Michael C, Walsh Dermot, O'Neill Anthony, Papadimitriou George N, Dikeos Dimitris, Maier Wolfgang, Lerer Bernard, Campion Dominique, Cohen David, Jay Maurice, Fanous Ayman, Eichhammer Peter, Silverman Jeremy M, Norton Nadine, Zhang Nancy, Hakonarson Hakon, Gao Cynthia, Citri Ami, Hansen Mark, Ripke Stephan, Dudbridge Frank, Holmans Peter A
Abstract excerpt
OBJECTIVE: The authors used a genome-wide association study (GWAS) of multiply affected families to investigate the association of schizophrenia to common single-nucleotide polymorphisms (SNPs) and rare copy number variants (CNVs). METHOD: The family sample included 2,461 individuals from 631 pedigrees (581 in the primary European-ancestry analyses). Association was tested for single SNPs and genetic pathways....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.