Article
Genetics of psychiatric disorders in the GWAS era: an update on schizophrenia.
European archives of psychiatry and clinical neuroscience - 1 Nov 2013
Schwab Sibylle G, Wildenauer Dieter B
Abstract excerpt
The influence of genetic factors in the development of schizophrenia has been convincingly demonstrated by family, twin, and adoption studies. The statistical construct of heritability is generally used for estimating the liability due to genetic factors. Heritability estimates for schizophrenia are reported to be between 60 and 80 %. Due to the technical achievements in whole genome-wide association studies,...
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