Article
Influence of serotonin transporter promoter variation on the effects of separation from parent/partner on depression.
Journal of affective disorders - 25 Jan 2013
Fandiño-Losada Andrés, Wei Yabin, Aberg Elin, Sjöholm Louise K, Lavebratt Catharina, Forsell Yvonne
Abstract excerpt
BACKGROUND: Loss of parent during childhood or loss of partner has been associated with adulthood depression. The serotonin transporter polymorphism (5-HTTLPR) has been reported to moderate stress sensitivity reflected for example in the relationship between childhood maltreatment and depression. Therefore, the effect of 5-HTT promoter variation on the relationship between the loss of parent or partner and...
Topics
- Adult
- Depression
- Depressive Disorder, Major
- Divorce
- Female
- Haplotypes
- Humans
- Life Change Events
- Male
- Middle Aged
- Object Attachment
- Odds Ratio
- Parents
- Polymorphism, Single Nucleotide
- Promoter Regions, Genetic