Article
The effect of a Beare-Stevenson syndrome Fgfr2 Y394C mutation on early craniofacial bone volume and relative bone mineral density in mice.
Journal of anatomy - 1 Nov 2012
Percival Christopher J, Wang Yingli, Zhou Xueyan, Jabs Ethylin W, Richtsmeier Joan T
Abstract excerpt
Quantifying the craniofacial skeletal phenotype during development highlights potential effects of known mutations on bone maturation and is an informative first step for the analysis of animal models. We introduce a novel technique to easily and efficiently quantify individual cranial bone volume and relative bone mineral density across the murine skull from high resolution computed tomography images. The...
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