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Article

Brain phenotypes in two FGFR2 mouse models for Apert syndrome.

Developmental dynamics : an official publication of the American Association of Anatomists - 1 Mar 2010

Aldridge Kristina, Hill Cheryl A, Austin Jordan R, Percival Christopher, Martinez-Abadias Neus, Neuberger Thomas, Wang Yingli, Jabs Ethylin Wang, Richtsmeier Joan T

Abstract excerpt

Apert syndrome (AS) is one of at least nine disorders considered members of the fibroblast growth factor receptor (FGFR) -1, -2, and -3-related craniosynostosis syndromes. Nearly 100% of individuals diagnosed with AS carry one of two neighboring mutations on Fgfr2. The cranial phenotype associated with these two mutations includes coronal suture synostosis, either unilateral (unicoronal synostosis) or bilateral...

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Share to Tomography, X-Ray Computed
Share to Acrocephalosyndactylia

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Gene Expression Regulation, Developmental

Share to Magnetic Resonance Spectroscopy

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Share to Receptor, Fibroblast Growth Factor, Type 2

Source

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Identifiers

PMID: 20077479
DOI: 10.1002/dvdy.22218
PMCID: PMC2829947

Genes

FGFR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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